Wednesday, 10 August 2016
Myoglobin
Myoglobin, a hemeprotein present in heart and skeletal muscle, functions both as a reservoir for oxygen, and as an oxygen carrier that increases the rate of transport of oxygen within the muscle cell.
Myoglobin consists of a single polypeptide chain that is structurally similar to the individual subunit polypeptide chains of the hemo globin molecule. This homology makes myoglobin a useful model for interpreting some of the more complex properties of hemoglobin.
Hemoglobin
Hemoglobin is found exclusively in red blood cells (RBCs), where its main function is to transport oxygen (O2) from the lungs to the capillaries of the tissues. Hemoglobin A, the major hemoglobin in adults, is composed of four polypeptide chains held together by noncovalent interactions.Each subunit has stretches of a helical structure, and a heme-binding pocket similar to that described for myoglobin. However, the tetrameric hemoglobin molecule is structurally and functionally more complex than myoglobin. For example, hemoglobin
Globular Protein
Hemeproteins are a group of specialized proteins that contain heme as a tightly bound prosthetic group. The role of the heme group is dictated by the environment created by the three-dimensional structure of the protein. In hemo globin and myoglobin, the two most abundant hemeproteins in humans, the heme group serves to reversibly bind oxygen.
Tuesday, 9 August 2016
Treatment of Iron Deficiency Anemia
There are some optional available to treat iron deficiency anemia such as supplements or foods.
This supplement can help restore the iron level in body. For the best impact, the patients need to take the supplement before meal (empty stomach) to increase the absorption. The supplement is needed for several months and may cause constipation. The most common supplement is ferrous sulphate.
Iron Deficiency Anemia
Iron deficiency anemia is the most common nutritional anemia. It occurs when your body does not have enough iron. Body needs iron to make RBCs and Hemoglobin. In body, Hb carry oxygen to your tissue. Also, you need oxygen to form energy (ATP). In children, iron deficiency anemia usually is caused by helminthes.
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